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nano-particle

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receptor - ligands interaction based on receptor density Those developing targeted drug therapies aim to recreate this precise binding to develop nano-sized drug carriers that attach only to diseased cells. Once attached, these carriers would release their therapeutic load without affecting healthy cells. If drugs can be specifically targeted in this way, treatments would cause far fewer side effects. One way to identify which cells are diseased is th..
nano-fish net trapping drug molecules Molecules found in nature, such as DNA and peptides, can rapidly self-assemble and organize into diverse structures. Mimicking this process using human-made polymer systems, however, has remained limited. Previously developed processes for self-assembling drug delivery systems are time consuming, labor intensive and difficult to scale. The processes also tend to be woefully inefficient, culminat..
Bone marrow targeted nano-particle RNA interference is a strategy that could potentially be used to treat a variety of diseases by delivering short strands of RNA that block specific genes from being turned on in a cell. So far, the biggest obstacle to this kind of therapy has been the difficulty in delivering it to the right part of the body. When injected into the bloodstream, nanoparticles carrying RNA tend to accumulate in th..
size determine interaction bwtn nanoparticles and membrane Imperial researchers have tested whether gold nanoparticles could be toxic to cells, finding how they affect lipid membranes depends on their size. Nanoparticles come in a wide variety of sizes, shapes and materials, and biological systems are complex, making determining how they interact with each other difficult to study. However, researchers know that one of the key first steps in toxicity is..
synthesize gold nano particles in cell demonstrates for the first time a method of biosynthesizing plasmonic gold nanoparticles within cancer cells, without the need for conventional bench-top lab methods. It has the potential to notably expand biomedical applications. Conventional laboratory-based synthesis of gold nanoparticles require ionic precursors and reducing agents subjected to varying reaction conditions such as temperature..
A high-yield method for nano-particle clusters 읽자 A team of researchers from China, the U.S. and Canada has developed a high-yield method for assembling targeted nanoparticle clusters. Over the past several decades, scientists have learned how to create nanoparticles—particles of matter that are between 1 and 100 nanometers in diameter—for a wide variety of purposes. They are currently created using one of several techniques. The most popular a..
DNA origami structure for detecting specific protein The molecules—known as biomarkers—are currently collected in their billions—if not trillions—in order to create a detectable signal of a disease. The new system, which has already been used to detect a protein linked to cystic fibrosis, can compile a detectable signal from just a few biomarkers, and can be done in just a few minutes. The new method involves using DNA origami—a nanoscale techniqu..
Leveraging mRNA Sequences for helping host to have antibody Scientists manipulated a natural cellular process to ramp up levels of two proteins used by the virus to infect other cells, packaged the protein-boosting instructions in nanoparticles and injected them into mice. Within a month, the mice had developed antibodies against the SARS-CoV-2 virus. The technique involves altering specific sequences of messenger RNA, molecules that translate genetic in..