CRISPR-based diagnostic for COVID-19

have been working on a CRISPR-based diagnostic for COVID-19 that can produce results in 30 minutes to an hour, with similar accuracy as the standard PCR diagnostics now used.

The new test, known as STOPCovid, is still in the research stage but, in principle, could be made cheaply enough that people could test themselves every day.

https://youtu.be/ZGZYhX4-xH4

In the new version of STOPCovid reported today, the researchers incorporated a process to concentrate the viral genetic material in a patient sample by adding magnetic beads that attract RNA, eliminating the need for expensive purification kits that are time-intensive and can be in short supply due to high demand. This concentration step boosted the test's sensitivity so that it now approaches that of PCR.

"Once we got the viral genomes onto the beads, we found that that could get us to very high levels of sensitivity," Gootenberg says.

 

팽짱 논문을 뽑아먹고 있다..

 

reference

Julia Joung et al, Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing, New England Journal of Medicine (2020). DOI: 10.1056/NEJMc2026172