2D 물질을 이용한 도파민 센서

A supersensitive dopamine detector can help in the early diagnosis of several disorders that result in too much or too little dopamine

Dopamine is an important neurotransmitter that can be used to diagnose disorders such as Parkinson's disease, Alzheimer's disease and schizophrenia.

Their work shows that by adding a small amount of manganese to a two-dimensional layered material called molybdenum disulfide, they can improve the sensitivity by many orders of magnitude compared to other reported results, while also achieving high specificity. Importantly, their detector is low-cost and flexible, and can detect dopamine in background media including buffer, serum and sweat, and in real-time.

n further work, the group hopes to find other material combinations to detect a variety of other biomarkers with the specificity of their current sensor. Creating such a "toolkit" combining experimental investigations with computational methods will lead to new materials with multifunctional capabilities. This might be useful beyond human health, for example, for detecting noxious gases, water contamination or biodefense agents.

 

집가서 읽어봐야겠다.

 

reference

"Single-atom doping of MoS2 with manganese enables ultrasensitive detection of dopamine: Experimental and computational approach" Science Advances (2020). advances.sciencemag.org/lookup … .1126/sciadv.abc4250