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cancer

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구조 세포와 면역반응의 관계 모르는 단어 hematopoietic: upregulation: in the biological context of organism's production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus. the complementary process that involves increases of such components is called upregulation. epigenetics: 유전자 자체에서의 변화가 아닌, 유전자 발현에서의 변화로 ..
deformed protein folder (chaperone)'s influence In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don't fold the way they're supposed to, it can lead to the development of diseases such as cancer. Researchers at the Sloan Kettering Institute have uncovered important findings about what causes chaperones to malfu..
PTB turn Astrocyte into neuron For decades, Fu and his team at University of California San Diego School of Medicine studied a protein called PTB, which is well known for binding RNA and influencing which genes are turned "on" or "off" in a cell. To study the role of a protein like PTB, scientists often manipulate cells to reduce the amount of that protein, and then watch to see what happens. Several years ago, a postdoctoral..
lipid가 아닌, RNA와 protein으로 vesicle만들기. These bubble-like entities—which form spontaneously when specific protein and RNA molecules are mixed in an aqueous buffer solution—hold potential as biological storage compartments. They could serve as an alternative to traditional vesicles that are made from water-insoluble organic compounds called lipids, researchers say. "Our discovery has widespread implications, from understanding basic ce..
protein that help migrate and grow of cancer cell Research has shown faulty or mutated versions of MET to be involved in cancer cell growth and spread in a variety of cancer types; however, the precise mechanisms by which it controls these processes are unknown. MET belongs to a group of proteins called receptor tyrosine kinases (RTKs), which are key regulatory proteins involved in a variety of signaling pathways that control normal cellular pr..
EV(Extracellular Vescicle)가 matrix를 거쳐갈 수 있는 mechanism https://phys.org/news/2020-06-unveils-mechanism-long-distance-cell.html An extracellular vesicle—a nanoparticle released by cells—can use jerky movements similar to a car weaving in and out of traffic to navigate the obstacle-filled environment outside of cells "Although EVs were discovered over 30 years ago, many believed that EVs were cellular junk that was trapped in the extracellular matrix,..
statin, inhibiting cancer cell metastasis https://medicalxpress.com/news/2020-06-common-cholesterol-drugs-breast-cancer.html A new study from the University of Notre Dame shows drugs used to treat high cholesterol could interfere with the way breast cancer cells adapt to the microenvironment in the brain, preventing the cancer from taking hold. Statins, a group of drugs commonly prescribed for those with high cholesterol, were shown to ..