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killing cancer by healing tissue Despite the remarkable successes of immune-based treatments for cancer, not everyone responds to these approaches and relapses do occur. According to Ming Li, an immunologist in the Sloan Kettering Institute, most existing immunotherapy approaches, including both checkpoint blockade and CAR T therapy, aim to prod the immune system into finding and killing cancer cells—a kind of frontal attack on..
Mass screening method cuts COVID-19 testing costs Tiny quantities taken from individual swabs were mixed to create combined samples and then tested. The team showed that a single positive case could still be detected even when mixed with 99 negative swab results. If this initial test highlighted that the mixed sample contained positive cases, then researchers used the algorithm to design a further series of tests. This enabled them to pinpoint ..
optofluidics for detecting brain injury A method for detecting traumatic brain injury at the point of care has been developed by scientists at the University of Birmingham. Using chemical biomarkers released by the brain immediately after a head injury occurs, researchers are able to pinpoint when patients need urgent medical attention. This saves time in delivering vital treatment and avoids patients undergoing unnecessary tests wher..
relationship between BBB & neural activity stm.sciencemag.org/content/12/564/eabe8119 it is commonly known that vascular function can affect neural activity; indeed, decreased brain perfusion impedes neural function. Conversely, neural activity can influence vascular function; for instance, neural activity induces blood flow changes, yielding the contrast mechanism of fMRI. A recent study by Pulido and colleagues has taken this story fur..
Electrodes as functional groups with tunable electronic properties several institutions in the Republic of Korea has found that it is possible to replace chemical functional groups with a gold electrode to control the reactivity of a molecule. the group describes attaching target molecules to a gold electrode to change the properties of immobilized molecules and how their technique performed when used to rate changes in the hydrolysis of certain esters. In chem..
biofilms destruct host membrane by mechanical stress The vast majority of bacteria in the world live on surfaces by forming structures called biofilms. These communities host thousands to millions of bacteria of different types, and are so biologically complex and active that scientists describe them as 'cities.' Biofilms are in fact the preferred lifestyle of bacteria. They form them by attaching to each other on surfaces as diverse as the ocean ..
simple nucleic acid extraction method - 읽어보자 Technology that helps to quickly extract and analyze genetic material could be used for cheap, accurate and mobile COVID-19 testing, including at airports and remote testing centers. 'Dipstick' technology, developed by the University of Queensland's Professor Jimmy Botella and Dr. Michael Mason, allows genetic material to be extracted in as little as 30 seconds, with a full molecular diagnosis i..
receptor - ligands interaction based on receptor density Those developing targeted drug therapies aim to recreate this precise binding to develop nano-sized drug carriers that attach only to diseased cells. Once attached, these carriers would release their therapeutic load without affecting healthy cells. If drugs can be specifically targeted in this way, treatments would cause far fewer side effects. One way to identify which cells are diseased is th..