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porous PDMS : biocompatible & permeable "Electronic-ECM: A Permeable Microporous Elastomer for an Advanced Bio-Integrated Continuous Sensing Platform," published in the journal Advanced Materials Technology. The study utilizes polydimethylsiloxane (PDMS), a silicone material popular for use in biosensors because of its biocompatibility and soft mechanics. It's generally utilized as a solid film, nonporous material, which can lead to p..
smart suit, using conductive thread Led by Assistant Professor John Ho, a team from the NUS Institute for Health Innovation and Technology, designed the pattern of the web-like threads to relay electromagnetic signals from a nearby smartphone to sensors on the body as far as a meter away, providing power and data connectivity across the suit. The team took about two years to develop the technology and its research findings were pu..
Astrocyte - BBB supporter Now, in a study with potential impacts on a variety of neurological diseases, Virginia Tech researchers have provided the first experimental evidence from a living organism to show that an abundant, star-shaped brain cell known as an astrocyte is essential for blood-brain barrier health. Furthermore, the finding gives scientists a path to understand diseases where frequent blood-brain barrier da..
depression and immune response An inflammatory autoimmune response within the central nervous system similar to one linked to neurodegenerative diseases such as multiple sclerosis (MS) has also been found in the spinal fluid of healthy people, according to a new Yale-led study comparing immune system cells in the spinal fluid of MS patients and healthy subjects. The research, published Sept. 18 in the journal Science Immunolo..
mechanism of COVID-19 receptor binding The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to research from the Francis Crick Institute published in Nature. The infection begins when a spike protein binds with ACE2 cell surface receptors and, at later stages, catalyzes the release of the virus genome into the ce..
size determine interaction bwtn nanoparticles and membrane Imperial researchers have tested whether gold nanoparticles could be toxic to cells, finding how they affect lipid membranes depends on their size. Nanoparticles come in a wide variety of sizes, shapes and materials, and biological systems are complex, making determining how they interact with each other difficult to study. However, researchers know that one of the key first steps in toxicity is..
CRISPR-based diagnostic for COVID-19 have been working on a CRISPR-based diagnostic for COVID-19 that can produce results in 30 minutes to an hour, with similar accuracy as the standard PCR diagnostics now used. The new test, known as STOPCovid, is still in the research stage but, in principle, could be made cheaply enough that people could test themselves every day. https://youtu.be/ZGZYhX4-xH4 In the new version of STOPCovid repo..
synthesize gold nano particles in cell demonstrates for the first time a method of biosynthesizing plasmonic gold nanoparticles within cancer cells, without the need for conventional bench-top lab methods. It has the potential to notably expand biomedical applications. Conventional laboratory-based synthesis of gold nanoparticles require ionic precursors and reducing agents subjected to varying reaction conditions such as temperature..