개인의 유전적 환경적 특성에 따른 음식의 반응 차이

https://medicalxpress.com/news/2020-06-paradigm-individual-effects-diet.html

In an article released today in the Nature Food journal, researchers show that people react differently to being fed exactly the same diet over a four-day period and that their urine contains different patterns of chemicals suggesting that we each have a unique response to diet.

although everyone consumed the same amount of calories, some people "excreted" more calories in their urine than others.

"The interaction between our genes and environment is complex and understanding the relationship between our metabolic response to diet is key to the prevention of chronic conditions such as obesity, heart disease and diabetes,"

 Several of the chemicals that changed in the urine were generated by the gut bacteria which is consistent with the fact that people have different gut bacteria and that these bacteria can use different foods as fuel."

"Based on the metabolic response to the four different diets, we were able to create a model that can predict the healthiness of a person's diet," Professor Holmes said. "We tested the model in two different populations and compared the chemical profiles to dietary records. This model will provide a framework for developing precision nutrition programs aimed at healthy weight loss or maintenance."

"We are in the process of implementing this tool in our dietitian clinics to improve the nutritional management of patients and we believe that this personalized approach will make a real difference to patients."

 

사람마다 microbiome이나 다른 특성들이 달라 같은 음식을 먹더라도 metabolic response가 다르다는 내용이다. 

이것을 통해 사람마다 식단을 다르게 해야된다는 것이 나왔다. 

 

reference

Isabel Garcia-Perez et al. Dietary metabotype modelling predicts individual responses to dietary interventions, Nature Food (2020). DOI: 10.1038/s43016-020-0092-z